I was reading in the university health news daily website that a study performed by researchers at the University of Texas . Anderson Cancer Center found that men with prostate cancer who ate 3 tablespoons of milled or ground flax seeds each day had decreased prostate cancer cell proliferation compared to similar men who did not eat flax seeds. According to the American Cancer Society, men who supplement their diets with flax seed have lower PSA levels and slower growth of benign as well as cancerous prostate cells.
Perhaps the effect of phytoestrogenic in humans it’s not fully understood as yet.
In a Caucasian boy with HSD10MD, Falk et al. (2016) identified a hemizygous missense mutation in the HSD17B10 gene (K212E; ). No parental DNA or DNA from reportedly affected maternal uncles was available for study. In vitro functional expression assays showed that the mutation resulted in decreased dehydrogenase activity. However, more significantly, the mutation disrupted TRMT10C ( 615423 )-associated methyltransferase activity and destabilized the RNase P holoenzyme, resulting in impaired mitochondrial tRNA processing and maturation and impaired mitochondrial protein synthesis. The findings suggested that the major pathogenic mechanism resulting from HSD17B10 mutations is the adverse effect on mitochondrial function.
Parmer et al. (1992) assessed baroreflex sensitivity in hypertensives with or without a positive family history of hypertension and in normotensives with or without a positive family history. This was done by recording cardiac slowing in response to acute phenylephrine-induced hypertension and cardiac acceleration in response to amyl nitrite-induced fall in blood pressure. Of all variables investigated, family history of hypertension was the strongest unique predictor of baroreflex sensitivity. Parmer et al. (1992) suggested that impairment in baroreflex sensitivity in hypertension is in part genetically determined and may be an important hereditary component in the pathogenesis of essential hypertension.