Resveratrol is a wine phenolic that is known to interact with sirtuin proteins (mostly SIRT1) which is similar to leucine; the metabolites of KIC and HMB at are able to induce SIRT1 to 30-100% of baseline which is a comparable potency to 2-10μM resveratrol  although the combination of leucine () or HMB (μM) and resveratrol (200nM) is able to synergistically induce SIRT1 and SIRT3 activity in both adipocytes and skeletal muscle cells.  KIC appears to be a more potent stimulator than HMB,  and synergism appears to be greater with leucine than with HMB (possibly indicative of KIC metabolism). 
Next week when i get back in the gym from my break i am going to be doing the BCAA/fasted-state protocol. I know stimulants like caffeine will be okay to take pre-workout. but what about amino acids such as tyrosine and ALCAR.
i'm noticed when i tried to take tyrosine in the ., but i feel as if i'm kicked out of the "Fasting state". so i now save it for the 8 hour window.
By taking in tyrosine and ALCAR pre-workout with the caffeine, then the BCAAs right before the workout. would that be pretty much altering the fasted state of the body?
I know it might not matter in the long-scheme of things, but i'm just curious lol. thanks
Hey Martin, thanks for keeping the posts coming I love your site. I have been doing IF for a few months now and train in a fasted state and I love it. My usual day is up at 7 work for 9 at Gym by 5:30pm and then start my window around 7pm, I realize I am not utilizing the 8 hour window completely but I find I don't need it. I am generally good eating one large meal at 7pm and then something again at 9pm. I do not have any problems with hunger and surprisingly my energy levels are much better than when I was doing that 6 meals a day junk. Recently the person I train with has switched jobs and it looks like our work outs will be pushed back to closer to 6:30pm or 7:00pm. My initial thought was that I will eat after work, go to the gym, and then eat again after the gym. The problem is I really enjoy fasted training and fear that if I eat pre-training I will get lazy and not have the drive that I have when I am fasted (it's like a subconscious goal to push hard to get to that meal when I train fasted). Would it be too much if I wasn't eating until 9pm some nights? because realistically I will be turning the 8 hour window into more of a 2 hour window and also will be eating right before I go to sleep which concerns me a bit. Maybe I am worrying to much! I love IF and trainging...to bad work gets in the way! haha.
any input would be appreciated.