Transdermal patches (adhesive patches placed on the skin) may also be used to deliver a steady dose through the skin and into the bloodstream. Testosterone-containing creams and gels that are applied daily to the skin are also available, but absorption is inefficient (roughly 10%, varying between individuals) and these treatments tend to be more expensive. Individuals who are especially physically active and/or bathe often may not be good candidates, since the medication can be washed off and may take up to six hours to be fully absorbed. There is also the risk that an intimate partner or child may come in contact with the application site and inadvertently dose himself or herself; children and women are highly sensitive to testosterone and can suffer unintended masculinization and health effects, even from small doses. Injection is the most common method used by individuals administering AAS for non-medical purposes. 
Sale is more dominant this year than he’s ever been. After his strikeout rate dipped to per nine innings last year, he has raised that mark to a career high per nine. As always seems to be the case, this puts him very close to entering a realm of pitching dominance only occupied by Randy Johnson and Pedro Martinez: Those are the only two pitchers to have pitched at least 150 innings in a season and struck out 13 batters per nine. (Martinez struck out per nine in 1999, and Johnson sat down per nine in 2001.) Sale has spent much of his career nearing milestones set by Martinez and Johnson—he took yet another run at Martinez’s nine-game streak with 10 or more strikeouts this year, and once again came up just one game short of tying it —and even if he doesn’t crack the 13 K/9 mark this year, would you bet against him getting there in the future?