Paracetamol versus non steroidal anti-inflammatory drugs for rheumatoid arthritis

A person's history of taking paracetamol is somewhat accurate for the diagnosis. [38] The most effective way to diagnose poisoning is by obtaining a blood paracetamol level. A drug nomogram developed in 1975, called the Rumack-Matthew nomogram , estimates the risk of toxicity based on the serum concentration of paracetamol at a given number of hours after ingestion. [8] To determine the risk of potential hepatotoxicity, the paracetamol level is traced along the nomogram. Use of a timed serum paracetamol level plotted on the nomogram appears to be the best marker indicating the potential for liver injury. [17] A paracetamol level drawn in the first four hours after ingestion may underestimate the amount in the system because paracetamol may still be in the process of being absorbed from the gastrointestinal tract . Therefore, a serum level taken before 4 hours is not recommended. [16]

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  • Citation tools Download this article to citation manager Little Paul , Moore Michael , Kelly Joanne , Williamson Ian , Leydon Geraldine , McDermott Lisa et al. Ibuprofen, paracetamol, and steam for patients with respiratory tract infections in primary care: pragmatic randomised factorial trial BMJ 2013; 347 :f6041
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    Paracetamol versus non steroidal anti-inflammatory drugs for rheumatoid arthritis

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