Various side effects are also reported with this medicine because it is a very powerful medicine. Most of the side effects are associated and related with misuse of this medicine therefore you should be cautious about it. Before using prednisone it is recommended to meet with your doctor so that he can provide you better information about it. Some side effects are also result due to prolonged use of this medicine. Side effects also results due to withdrawal of this medicine. Withdrawal of prednisone is not easy instead it is a very difficult task. There are many types of withdrawal symptoms like headache, obesity, suppression of appetite and many others. Therefore it is recommended to use this medicine in small doses and quantity. With the passage of time it is better to reduce its dosage so that you can avoid from its side effects. It is also better to use it as it is prescribed to you by doctor.